Just bought a Wacom Pen and Touch tablet. Natural scrolling works the same as Apple in the vertical direction, but opposite in the horizontal. So imagine pressing 'Z' in Aperture then:
push up moves the canvas up; down moves it down
push right moves it LEFT and push left moves it RIGHT
I'm running Lion 10.7.4 which has been freshly installed a week ago on a 24-inch iMac that I zapped and reinstalled from scratch a fortnight ago, so it's almost pristine. Wacom's user forum is full of (slightly different) complaints about lack of OS X compatibility and it seems Wacom aren't addressing any of them.
Any thoughts before I send the wretched thing back?